
Below is an example of wing design based on "fixing" a span load
distribution. When the 737 was re-engined with high bypass ratio turbofans,
a drag penalty was avoided by changing the effective wing twist distribution.

The details of the pressure distribution can then be used to modify the
camber shape or wing thickness for best performance. This sounds straightforward,
but it is often very difficult to accomplish this, especially when it takes
hours or days to examine the effect of the proposed change. This is why
simple methods with fast turnaround times are still used in the wing design
process.

As computers become faster, it becomes more feasible to do full 3-D optimization.
One of the early efforts in applying optimization and nonlinear CFD to wing
design is described by Cosentino and Holst, J. of Aircraft, 1986.
In this problem, a few spline points at several stations on the wing were
allowed to move and the optimizer tried to maximize L/D.

Although this was an inviscid code, the design variables were limited, and
the objective function simplistic, current research has included more realistic
objectives, more design degrees of freedom, and better analysis codes.

--but we are still a long way from having "wings designed by computer."